Please respect the rules of the Challenge. The organization reserves the right to not consider submissions that fail to abide to the rules presented in this page:


Both individual and team participations are welcome in the Challenge. This Challenge is part of the 16th European Congress on Digital Pathology (ECDP2020). For each team, at least one person must be registered in the congress to be eligible to the challenge's prizes. 

The contact information provided will not be used for any purposes other than those related to the congress or this Challenge.

Once the registration is completed and accepted, participants will receive instructions on how to download the dataset.

Please note that each person can only belong to one team.

Registration links: 


Participation in the Challenge is conditioned to the proper submission of:

  1. a short method description, and the code (or compiled version*) until December 31st, 2019
  2. the predictions until January 15th, 2020

To be eligible for the prizes, it is also mandatory that at least one member of each team properly register and attend ECDP2020.

Results will be made publicly available on the Challenge website after the submission deadline.

Challenge participants grant the Challenge organization the permission to use the result of their methods. Nevertheless, participating teams maintain full ownership and rights to their method. The Challenge organization does not claim any ownership or rights to the developed works.

The best performing methods will be invited to collaborate on a journal paper describing and summarizing the different approaches used and the respective results achieved on the Challenge.

To ensure a fair comparison of the submitted methods, the usage of any private dataset during the development of the methods is not allowed.

Note that submission of a result in the Grand Challenge HEROHE does not warrant the presentation of a poster/oral presentation at ECDP2020. Each team is encouraged to submit their work as an abstract according to the abstract submission rules of ECDP2020.

* If the team decides to provide only a compiled version, it is their sole responsibility to ensure that it is ready to run on all major operating systems.


The presented dataset contains 360 cases, 144 positives and 216 negatives. Each whole-slide image was saved in the  MIRAX format.

For more information please the Dataset page.


The downloaded dataset, or any data derived from this dataset, cannot be given or redistributed under any circumstances to persons not belonging to the registered team.

This dataset was designed for being used exclusively in the context of the HEROHE Grand-Challenge and / or the submission of communications to the ECDP2020. The dataset, or any data derived from this dataset, cannot be used for any other purposes, including but not limited to military, industrial development/patenting, or academic use (including journal publications, conference papers, technical reports, presentations at conferences and meetings or teaching).

The organization anticipates that the results of this challenge will be published in an international peer-reviewed scientific journal. If and when this happens, the dataset will become available for research purposes under the Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0). The corresponding publication should thus be cited. Updates on this issue will become available in the challenge web page.


Submission is to be performed in two stages. Until December 31st, 2019, each participant or team has to submit a short method description, and the code (see Participation Section). Until January 15, 2020 the predictions on the test dataset has to be submitted.

This submission will be used to rank the methods for prize distribution.

Note that each team can only participate in the challenge once, i.e., each team can only submit an algorithm. If several attempts of submission are performed, only the last will be considered.


The Challenge prizes will be awarded during the ECDP2020 conference, to be held in Porto, 13th-15th May 2020. Specifically,  ECDP2020  has allocated prizes to be distributed among the three teams with the best performance.

Eligibility to the Challenge's prizes is conditioned to the quality of the method and participation at the conference.


Submissions are scored based on the F1-score,  the harmonic mean of precision and recall: